Hydrogen Sulfide in Pharmacotherapy, Beyond the Hydrogen Sulfide-Donors
نویسندگان
چکیده
منابع مشابه
Bronchodilatory Effect of Hydrogen Sulfide in Rat
Objective(s) The aims of present study were to elucidate the effect of NaHS as a H2S donor on precontracted rat trachea smooth muscle, role of epithelium and nitric oxide in this action. Materials and Methods Tracheal rings from male adult Wistar rats were isolated and mounted in an organ bath containing Krebs–Henseleit solution under 1.5 g resting tension and contractions were recorded isom...
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Background: Hydrogen sulfide (H2S) suicides have been frequent in Japan in recent years. This study was performed to describe the epidemiologic profile of an outbreak of H2S suicides in Japan. Methods: In September 2008, questionnaires about patients involved in H2S suicides were sent to 250 hospitals in Japan. Data collected from each patient included gender, age, clinical manifestations, date...
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The measurement of sulfide, especially hydrogen sulfide, has held the attention of the analytical community due to its unique physiological and pathophysiological roles in biological systems. Electrochemical detection offers a rapid, highly sensitive, affordable, simple, and real-time technique to measure hydrogen sulfide concentration, which has been a well-documented and reliable method. This...
متن کاملSynthesis and evaluation of phosphorodithioate-based hydrogen sulfide donors.
A series of O-aryl- and alkyl-substituted phosphorodithioates were designed and synthesized as hydrogen sulfide (H2S) donors. H2S releasing capability of these compounds was evaluated using fluorescence methods. O-aryl substituted donors showed slow and sustained H2S release while O-alkylated compounds showed very weak H2S releasing capability. We also evaluated donors' protective effects again...
متن کاملbronchodilatory effect of hydrogen sulfide in rat
objective(s) the aims of present study were to elucidate the effect of nahs as a h2s donor on precontracted rat trachea smooth muscle, role of epithelium and nitric oxide in this action. materials and methods tracheal rings from male adult wistar rats were isolated and mounted in an organ bath containing krebs–henseleit solution under 1.5 g resting tension and contractions were recorded isometr...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2020
ISSN: 2218-273X
DOI: 10.3390/biom10020323